Assessing the impacts of environmental change on soil erosion and sediment yield at the large catchment scale remains one of the main challenges in soil erosion modelling studies. Here, we present a process-based soil erosion model, based on the integration of the Morgan–Morgan–Finney erosion model in a daily based hydrological model. The model overcomes many of the limitations of previous large-scale soil erosion models, as it includes a more complete representation of crucial processes like surface runoff generation, dynamic vegetation development, and sediment deposition, and runs at the catchment scale with a daily time step. This makes the model especially suited for the evaluation of the impacts of environmental change on soil erosion and sediment yield at regional scales and over decadal periods. The model was successfully applied in a large catchment in southeastern Spain. We demonstrate the model’s capacity to perform impact assessments of environmental change scenarios, specifically simulating the scenario impacts of intra- and inter-annual variations in climate, land management, and vegetation development on soil erosion and sediment yield.